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A model for the molecular underpinnings of tooth defects in Axenfeld–Rieger syndrome
Patients with Axenfeld–Rieger Syndrome (ARS) present various dental abnormalities, including hypodontia, and enamel hypoplasia. ARS is genetically associated with mutations in the PITX2 gene, which encodes one of the earliest transcription factors to initiate tooth development. Thus, Pitx2 has long...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857954/ https://ncbi.nlm.nih.gov/pubmed/23975681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt411 |
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