Awake Nonhuman Primate Brain PET Imaging with Minimal Head Restraint: Evaluation of GABA(A) Benzodiazepine Binding with [(11)C]Flumazenil in Awake and Anesthetized Animals

Neuroreceptor imaging in the nonhuman primate (NHP) is valuable for translational research approaches in humans. However, the majority of NHP studies are conducted under anesthesia, which affects the interpretability of receptor binding measures. The aims of this study are to develop awake NHP imagi...

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Auteurs principaux: Sandiego, Christine M., Jin, Xiao, Mulnix, Tim, Fowles, Krista, Labaree, David, Ropchan, Jim, Huang, Yiyun, Cosgrove, Kelly, Castner, Stacy A., Williams, Graham V., Wells, Lisa, Rabiner, Eugenii A., Carson, Richard E.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857935/
https://ncbi.nlm.nih.gov/pubmed/24115528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.122077
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