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Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination.

A procedure of reversible immortalization of primary cells was devised by retrovirus-mediated transfer of an oncogene that could be subsequently excised by site-specific recombination. This study focused on the early stages of immortalization: global induction of proliferation and life span extensio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Westerman, K A, Leboulch, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38579/
https://ncbi.nlm.nih.gov/pubmed/8799138
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