Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination.
A procedure of reversible immortalization of primary cells was devised by retrovirus-mediated transfer of an oncogene that could be subsequently excised by site-specific recombination. This study focused on the early stages of immortalization: global induction of proliferation and life span extensio...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38579/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8799138/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.17.8971 |
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