Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation

BACKGROUND: Lipotoxicity is a key feature of the pathogenesis of diabetic kidney disease, and is attributed to excessive lipid accumulation (hyperlipidemia). Increasing evidence suggests that fibroblast growth factor (FGF)21 has a crucial role in lipid metabolism under diabetic conditions. OBJECTIVE...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Zhang, Chi, Shao, Minglong, Yang, Hong, Chen, Liangmiao, Yu, Lechu, Cong, Weitao, Tian, Haishan, Zhang, Fangfang, Cheng, Peng, Jin, Litai, Tan, Yi, Li, Xiaokun, Cai, Lu, Lu, Xuemian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857822/
https://ncbi.nlm.nih.gov/pubmed/24349242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082275
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items