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Iterative Reducible Ligation to form Homogeneous Penicillamine Cross-linked Polypeptides

The syntheses of homogeneous penicillamine disulfide cross-linked polypeptides are reported. Dodecapeptides containing N-terminal, C-terminal, or N- and C-terminal Pen were serially ligated into 36 amino acid polypeptides linked through Cys-Pen, Pen-Cys or Pen-Pen disulfide bonds. Critical to the sy...

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Detalhes bibliográficos
Main Authors: Ericson, Mark D., Rice, Kevin G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857801/
https://ncbi.nlm.nih.gov/pubmed/24347694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.04.086
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