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Thymidylate Synthase in Situ Protein Expression and Survival in Stage I Nonsmall-Cell Lung Cancer

BACKGROUND: Thymidylate synthase (TS) is important for maintenance of the intracellular thymidine pool, which is crucial for DNA synthesis and repair. TS messenger RNA and protein levels are predictive of response to 5-fluorouracil-containing therapy for patients with colorectal cancer and gastric c...

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Autors principals: Zheng, Zhong, Li, Xueli, Schell, Michael J., Chen, Tingan, Boulware, David, Robinson, Lary, Sommers, Eric, Bepler, Gerold
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857609/
https://ncbi.nlm.nih.gov/pubmed/18442042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23491
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