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Oleanolic acid alters bile acid metabolism and produces cholestatic liver injury in mice
Oleanolic acid (OA) is a triterpenoids that exists widely in plants. OA is effective in protecting against hepatotoxicants. Whereas a low dose of OA is hepatoprotective, higher doses and longer-term use of OA produce liver injury. This study characterized OA-induced liver injury in mice. Adult C57BL...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3857557/ https://ncbi.nlm.nih.gov/pubmed/23948738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.08.003 |
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