Amifostine Protects Vascularity and Improves Unions in a Model of Irradiated Mandibular Fracture Healing

BACKGROUND: Pathologic fractures after irradiation (XRT) can be a devastating problem for cancer patients as XRT has a pernicious effect on bone healing in a large part due to impairment of vascularity. Our aim is to ascertain whether Amifostine (AMF), a radio-protective drug, will preserve the vasc...

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Main Authors: Sarhaddi, Deniz, Tchanque-Fossuo, Catherine N., Poushanchi, Behdod, Donneys, Alexis, Deshpande, Sagar S., Weiss, Daniela M., Buchman, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857216/
https://ncbi.nlm.nih.gov/pubmed/24281582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PRS.0b013e3182a80766
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