Amifostine Prophylaxis on Bone Densitometry, Biomechanical Strength and Union in Mandibular Pathologic Fracture Repair

BACKGROUND: Pathologic fractures (Fx) of the mandibles are severely debilitating consequences of radiation (XRT) in the treatment of craniofacial malignancy. We have previously demonstrated Amifostine’s effect (AMF) in the remediation of radiation-induced cellular damage. We posit that AMF prophylax...

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Main Authors: Tchanque-Fossuo, Catherine N., Donneys, Alexis, Sarhaddi, Deniz, Poushanchi, Behdod, Deshpande, Sagar S., Weiss, Daniela M., Buchman, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804002/
https://ncbi.nlm.nih.gov/pubmed/23860272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2013.07.005
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