The α and Δ Isoforms of CREB1 Are Required to Maintain Normal Pulmonary Vascular Resistance

Chronic hypoxia causes pulmonary hypertension associated with structural alterations in pulmonary vessels and sustained vasoconstriction. The transcriptional mechanisms responsible for these distinctive changes are unclear. We have previously reported that CREB1 is activated in the lung in response...

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Detalhes bibliográficos
Main Authors: Li, Lili, Howell, Katherine, Sands, Michelle, Banahan, Mark, Frohlich, Stephen, Rowan, Simon C., Neary, Roisín, Ryan, Donal, McLoughlin, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857174/
https://ncbi.nlm.nih.gov/pubmed/24349008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080637
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