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Gremlin 1 blocks vascular endothelial growth factor signaling in the pulmonary microvascular endothelium
The bone morphogenetic protein (BMP) antagonist gremlin 1 plays a central role in the pathogenesis of hypoxic pulmonary hypertension (HPH). Recently, non-canonical functions of gremlin 1 have been identified, including specific binding to the vascular endothelial growth factor receptor-2 (VEGFR2). W...
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| Published in: | Pulm Circ |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7066471/ https://ncbi.nlm.nih.gov/pubmed/30284507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045894018807205 |
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