Synergistic Activation of Inflammatory Cytokine Genes by Interferon-γ-induced Chromatin Remodeling and Toll-like Receptor Signaling

Synergistic activation of inflammatory cytokine genes by interferon-γ (IFN-γ) and Toll-like receptor (TLR) signaling is important for innate immunity and inflammatory disease pathogenesis. Enhancement of TLR signaling, a previously proposed mechanism, is insufficient to explain strong synergistic ac...

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Bibliographic Details
Main Authors: Qiao, Yu, Giannopoulou, Eugenia G., Chan, Chun Hin, Park, Sung-ho, Gong, Shiaoching, Chen, Janice, Hu, Xiaoyu, Elemento, Olivier, Ivashkiv, Lionel B.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857147/
https://ncbi.nlm.nih.gov/pubmed/24012417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.08.009
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