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Interplay Among Subunit Identity, Subunit Proportion, Chain Length and Stereochemistry in the Activity Profile of Sequence-Random Peptide Mixtures

Fmoc-based solid-phase synthesis methodology was used to prepare peptide mixtures containing one type of hydrophobic residue and one type of cationic residue. Each mixture was random in terms of sequence, but highly controlled in terms of length. Analysis of the antibacterial and hemolytic propertie...

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Detalhes bibliográficos
Main Authors: Hayouka, Zvi, Chakraborty, Saswata, Liu, Runhui, Boersma, Melissa D., Weisblum, Bernard, Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856984/
https://ncbi.nlm.nih.gov/pubmed/23909610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja406231b
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