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Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers

Nylon-3 co-polymers containing both hydrophobic and cationic subunits can mimic the activity profile of host-defense peptides, if subunit identity and proportion are carefully selected. These sequence- and stereo-random co-polymers inhibit bacterial growth at relatively low concentrations, apparentl...

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Detalhes bibliográficos
Main Authors: Chakraborty, Saswata, Liu, Runhui, Lemke, Justin J., Hayouka, Zvi, Welch, Rodney A., Weisblum, Bernard, Masters, Kristyn S., Gellman, Samuel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856927/
https://ncbi.nlm.nih.gov/pubmed/24349873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mz400239r
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