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The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

In vitro and in vivo resistance to prednisolone are predictive for an adverse prognosis in pediatric precursor B-acute lymphoblastic leukemia. Causes of resistance are still poorly understood. In this study, we observed that prednisolone exposure of prednisolone-sensitive patients’ leukemic cells de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ariës, Ingrid M., Hansen, Bo R., Koch, Troels, van den Dungen, Rosanna, Evans, William E., Pieters, Rob, den Boer, Monique L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856966/
https://ncbi.nlm.nih.gov/pubmed/24142999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.093823
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