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The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

In vitro and in vivo resistance to prednisolone are predictive for an adverse prognosis in pediatric precursor B-acute lymphoblastic leukemia. Causes of resistance are still poorly understood. In this study, we observed that prednisolone exposure of prednisolone-sensitive patients’ leukemic cells de...

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Detalhes bibliográficos
Main Authors: Ariës, Ingrid M., Hansen, Bo R., Koch, Troels, van den Dungen, Rosanna, Evans, William E., Pieters, Rob, den Boer, Monique L.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856966/
https://ncbi.nlm.nih.gov/pubmed/24142999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.093823
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