CNS-Resident Glial Progenitor/Stem Cells Produce Schwann Cells as well as Oligodendrocytes during Repair of CNS Demyelination

After central nervous system (CNS) demyelination—such as occurs during multiple sclerosis—there is often spontaneous regeneration of myelin sheaths, mainly by oligodendrocytes but also by Schwann cells. The origins of the remyelinating cells have not previously been established. We have used Cre-lox...

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Main Authors: Zawadzka, Malgorzata, Rivers, Leanne E., Fancy, Stephen P.J., Zhao, Chao, Tripathi, Richa, Jamen, Françoise, Young, Kaylene, Goncharevich, Alexander, Pohl, Hartmut, Rizzi, Matteo, Rowitch, David H., Kessaris, Nicoletta, Suter, Ueli, Richardson, William D., Franklin, Robin J.M.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856868/
https://ncbi.nlm.nih.gov/pubmed/20569695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.04.002
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