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Dimerization of LTβR by LTα(1)β(2) is necessary and sufficient for signal transduction
Homotrimeric TNF superfamily ligands signal by inducing trimers of their cognate receptors. As a biologically active heterotrimer, Lymphotoxin(LT)α(1)β(2) is unique in the TNF superfamily. How the three unique potential receptor-binding interfaces in LTα(1)β(2) trigger signaling via LTβ Receptor (LT...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856818/ https://ncbi.nlm.nih.gov/pubmed/24248355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310838110 |
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