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NFATc1 and NFATc2 repress spontaneous osteoarthritis

Osteoarthritis (OA) was once viewed originally as a mechanical disease of “wear and tear,” but advances made during the past two decades suggest that abnormal biomechanics contribute to active dysregulation of chondrocyte biology, leading to catabolism of the cartilage matrix. A number of signaling...

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Autores principales: Greenblatt, Matthew B., Ritter, Susan Y., Wright, John, Tsang, Kelly, Hu, Dorothy, Glimcher, Laurie H., Aliprantis, Antonios O.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856808/
https://ncbi.nlm.nih.gov/pubmed/24248346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320036110
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