RNA-sequencing from single nuclei

It has recently been established that synthesis of double-stranded cDNA can be done from a single cell for use in DNA sequencing. Global gene expression can be quantified from the number of reads mapping to each gene, and mutations and mRNA splicing variants determined from the sequence reads. Here...

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Detalhes bibliográficos
Main Authors: Grindberg, Rashel V., Yee-Greenbaum, Joyclyn L., McConnell, Michael J., Novotny, Mark, O’Shaughnessy, Andy L., Lambert, Georgina M., Araúzo-Bravo, Marcos J., Lee, Jun, Fishman, Max, Robbins, Gillian E., Lin, Xiaoying, Venepally, Pratap, Badger, Jonathan H., Galbraith, David W., Gage, Fred H., Lasken, Roger S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856806/
https://ncbi.nlm.nih.gov/pubmed/24248345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319700110
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