Cis-Acting Regulation of Brain-Specific ANK3 Gene Expression by a Genetic Variant Associated with Bipolar Disorder

Several genome-wide association studies (GWAS) for bipolar disorder (BD) have found a strong association of the Ankyrin3 (ANK3) gene. This association spans numerous linked single nucleotide polymorphisms (SNPs) in a ~250 kb genomic region overlapping ANK3. The associated region encompasses predicte...

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Main Authors: Rueckert, Erroll H., Barker, Douglas, Ruderfer, Douglas, Bergen, Sarah E., O’Dushlaine, Colm, Luce, Catherine J., Sheridan, Steven D., Theriault, Kraig M., Chambert, Kimberly, Moran, Jennifer, Purcell, Shaun, Madison, Jon M., Haggarty, Stephen J., Sklar, Pamela
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856665/
https://ncbi.nlm.nih.gov/pubmed/22850628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2012.104
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