Photoactivatable Drug-Caged Fluorophore Conjugate Allows Direct Quantification of Intracellular Drug Transport

We report here a method that utilizes photoactivatable drug-caged fluorophore conjugate to quantify intracellular drug trafficking processes at single cell resolution. Photoactivation is performed in labeled cellular compartments to visualize intracellular drug exchange at physiologic conditions, wi...

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Bibliographic Details
Main Authors: Agasti, Sarit S., Laughney, Ashley M., Kohler, Rainer H., Weissleder, Ralph
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856557/
https://ncbi.nlm.nih.gov/pubmed/24135896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc46089d
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