Development and Validation of Sensitive Liquid Chromatography/Tandem Mass Spectrometry Methods for Quantification of Bendamustine in Mouse Brain Tissue

A liquid chromatography-tandem mass spectrometry method for quantification of bendamustine in mouse brain tissue was developed and fully validated. Methanol was used to precipitate proteins in brain tissue. Bendamustine and internal standard (chlorambucil) were separated with reverse phase chromatog...

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Hlavní autoři: He, Lei, Grecula, John C., Ling, Yonghua, Enzerra, Michael D., Ammirati, Mario, Kendra, Kari, Cavaliere, Robert, Mayr, Nina, McGregor, John, Olencki, Thomas, Mrozek, Ewa, Matharbootham, Mani, Oluigbo, Chima, Phelps, Mitch A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856370/
https://ncbi.nlm.nih.gov/pubmed/22925718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2012.08.013
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