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PARN mediates 3′-end trimming of Argonaute2-cleaved precursor microRNAs
microRNAs (miRNAs) are typically generated as ~22-nucleotide double-stranded RNAs via processing of precursor hairpins by the RNase III enzyme Dicer, after which they are loaded into Argonaute (Ago) proteins to form RNA-induced silencing complex (RISC). However, the biogenesis of miR-451, an erythro...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3856240/ https://ncbi.nlm.nih.gov/pubmed/24209750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.029 |
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