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A genome-wide inducible phenotypic screen identifies antisense RNA constructs silencing Escherichia coli essential genes

Regulated antisense RNA (asRNA) expression has been employed successfully in Gram-positive bacteria for genome-wide essential gene identification and drug target determination. However, there have been no published reports describing the application of asRNA gene silencing for comprehensive analyses...

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Detalhes bibliográficos
Main Authors: Meng, Jia, Kanzaki, Gregory, Meas, Diane, Lam, Christopher K., Crummer, Heather, Tain, Justina, Xu, H. Howard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855647/
https://ncbi.nlm.nih.gov/pubmed/22268863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1574-6968.2012.02503.x
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