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Magnesium impacts myosin V motor activity by altering key conformational changes in the mechanochemical cycle

We investigated how magnesium (Mg) impacts key conformational changes during the ADP binding/release steps in myosin V and how these alterations impact the actomyosin mechanochemical cycle. The conformation of the nucleotide binding pocket was examined with our established FRET system in which myosi...

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Detalhes bibliográficos
Main Authors: Trivedi, Darshan, Muretta, Joseph M., Swenson, Anja M., Thomas, David D., Yengo, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855573/
https://ncbi.nlm.nih.gov/pubmed/23725637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4004364
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