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The TFPI-2 Derived Peptide EDC34 Improves Outcome of Gram-Negative Sepsis

Sepsis is characterized by a dysregulated host-pathogen response, leading to high cytokine levels, excessive coagulation and failure to eradicate invasive bacteria. Novel therapeutic strategies that address crucial pathogenetic steps during infection are urgently needed. Here, we describe novel bioa...

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Bibliografiske detaljer
Main Authors: Papareddy, Praveen, Kalle, Martina, Sørensen, Ole E., Malmsten, Martin, Mörgelin, Matthias, Schmidtchen, Artur
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855554/
https://ncbi.nlm.nih.gov/pubmed/24339780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003803
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