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Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey

The rat CNS contains high levels of tyrosine-specific protein kinases that specifically phosphorylate the tyrosine-containing synthetic peptide poly(Glu(80), Tyr(20)). The phosphorylation of this peptide is rapid and occurs with normal Michaelis–Menten kinetics. Using this peptide to assay for enzym...

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Detalhes bibliográficos
Main Authors: Hirano, Arlene A., Greengard, Paul, Huganir, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855467/
https://ncbi.nlm.nih.gov/pubmed/2452235
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