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Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra Performance Liquid Chromatography

INTRODUCTION: Grapefruit juice can increase or decrease the systemic exposure of myriad oral medications, leading to untoward effects or reduced efficacy. Furanocoumarins in grapefruit juice have been established as inhibitors of cytochrome P450 3A (CYP3A)-mediated metabolism and P-glycoprotein (P-g...

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書誌詳細
主要な著者: VanderMolen, Karen M., Cech, Nadja B., Paine, Mary F., Oberlies, Nicholas H.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855432/
https://ncbi.nlm.nih.gov/pubmed/23780830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pca.2449
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