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Down-regulation of BMPR Axis during HIV-1 and Cocaine-mediated Pulmonary Smooth Muscle Hyperplasia: Implications for HRPAH

OBJECTIVE: Our previous findings support an additive effect of cocaine to HIV-infection in the development of pulmonary arteriopathy through enhanced proliferation of human pulmonary smooth muscle cells. We now examined the role of anti-proliferative bone morphogenetic protein receptor (BMPR) axis i...

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Main Authors: Dalvi, Pranjali, O’Brien-Ladner, Amy, Dhillon, Navneet K.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855352/
https://ncbi.nlm.nih.gov/pubmed/24008158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302054
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