The Ets transcription factor GABP is a novel component of the Hippo pathway essential for growth and antioxidant defense

The transcriptional co-activator YAP plays an important role in organ size control and tumorigenesis. However, how Yap gene expression is regulated remains unknown. This study shows that the Ets family member GABP binds to the Yap promoter and activates YAP transcription. The depletion of GABP downr...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wu, Hongtan, Xiao, Yubo, Zhang, Shihao, Ji, Suyuan, Wei, Luyao, Fan, Fuqin, Geng, Jing, Tian, Jing, Sun, Xiufeng, Qin, Funiu, Jin, Changnan, Lin, Jianjun, Yin, Zhen-Yu, Zhang, Ting, Luo, Lianzhong, Li, Yang, Song, Siyang, Lin, Sheng-Cai, Deng, Xianming, Camargo, Fernando, Avruch, Joseph, Chen, Lanfen, Zhou, Dawang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855275/
https://ncbi.nlm.nih.gov/pubmed/23684612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.020
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge