The Ets transcription factor GABP is a novel component of the Hippo pathway essential for growth and antioxidant defense

The transcriptional co-activator YAP plays an important role in organ size control and tumorigenesis. However, how Yap gene expression is regulated remains unknown. This study shows that the Ets family member GABP binds to the Yap promoter and activates YAP transcription. The depletion of GABP downr...

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Main Authors: Wu, Hongtan, Xiao, Yubo, Zhang, Shihao, Ji, Suyuan, Wei, Luyao, Fan, Fuqin, Geng, Jing, Tian, Jing, Sun, Xiufeng, Qin, Funiu, Jin, Changnan, Lin, Jianjun, Yin, Zhen-Yu, Zhang, Ting, Luo, Lianzhong, Li, Yang, Song, Siyang, Lin, Sheng-Cai, Deng, Xianming, Camargo, Fernando, Avruch, Joseph, Chen, Lanfen, Zhou, Dawang
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855275/
https://ncbi.nlm.nih.gov/pubmed/23684612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.020
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