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Protein Phosphatase 4 and Smek complex negatively regulate Par3 and promote neuronal differentiation of neural stem/progenitor cells

Neural progenitor cells (NPCs) are multipotent cells that can self-renew and differentiate into neurons and glial cells. However, mechanisms that control their fate decisions are poorly understood. Here, we show that Smek1, a regulatory subunit of the serine/threonine protein phosphatase PP4, promot...

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Detalhes bibliográficos
Main Authors: Lyu, Jungmook, Kim, Hee-Ryang, Yamamoto, Vicky, Choi, Si Ho, Wei, Zong, Joo, Choun-Ki, Lu, Wange
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855259/
https://ncbi.nlm.nih.gov/pubmed/24209749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.09.034
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