CCAAT/Enhancer-Binding Protein Homologous (CHOP) Protein Promotes Carcinogenesis in the DEN-Induced Hepatocellular Carcinoma Model

BACKGROUND AND AIMS: C/EBP homologous protein (CHOP) plays pro-apoptotic roles in the integrated stress response. Recently, a tumor suppressive role for CHOP was demonstrated in lung cancer via regulation of tumor metabolism. To explore the role of CHOP in hepatocarcinogenesis, we induced hepatocell...

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Main Authors: Scaiewicz, Viviana, Nahmias, Avital, Chung, Raymond T., Mueller, Tobias, Tirosh, Boaz, Shibolet, Oren
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855209/
https://ncbi.nlm.nih.gov/pubmed/24339898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081065
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