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Prenatal corticosteroids modify glutamatergic and GABAergic synapse genomic fabric: Insights from a novel animal model of infantile spasms

Prenatal exposure to corticosteroids has long-term postnatal somatic and neurodevelopmental consequences. Animal studies indicate that corticosteroid exposure-associated alterations in the nervous system include hypothalamic function. Infants with infantile spasms, a devastating epileptic syndrome o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Iacobas, D.A., Iacobas, S., Chachua, T., Goletiani, C., Sidyelyeva, G., Velíšková, J., Velíšek, L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855178/
https://ncbi.nlm.nih.gov/pubmed/23763471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jne.12061
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