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ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms

We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline followed...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Iacobaş, Dumitru A., Chachua, Tamar, Iacobaş, Sanda, Benson, Melissa J., Borges, Karin, Velíšková, Jana, Velíšek, Libor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893534/
https://ncbi.nlm.nih.gov/pubmed/29636502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24013-x
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