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ACTH and PMX53 recover synaptic transcriptome alterations in a rat model of infantile spasms

We profiled the gene expression in the hypothalamic arcuate nuclei (ARC) of 20 male and 20 female rats to determine the infantile spasms (IS) related transcriptomic alteration of neurotransmission and recovery following two treatments. Rats were prenatally exposed to betamethasone or saline followed...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Iacobaş, Dumitru A., Chachua, Tamar, Iacobaş, Sanda, Benson, Melissa J., Borges, Karin, Velíšková, Jana, Velíšek, Libor
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5893534/
https://ncbi.nlm.nih.gov/pubmed/29636502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-24013-x
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