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PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response()

The protein phosphatase 1-like gene (PPM1l) was identified as causal gene for obesity and metabolic abnormalities in mice. However, the underlying mechanisms were unknown. In this report, we find PPM1l encodes an endoplasmic reticulum (ER) membrane targeted protein phosphatase (PP2Ce) and has specif...

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Detaylı Bibliyografya
Asıl Yazarlar: Lu, Gang, Ota, Asuka, Ren, Shuxun, Franklin, Sarah, Rau, Christoph D., Ping, Peipei, Lane, Timothy F., Zhou, Z. Hong, Reue, Karen, Lusis, Aldons J., Vondriska, Thomas, Wang, Yibin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854994/
https://ncbi.nlm.nih.gov/pubmed/24327956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.07.005
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