PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response()

The protein phosphatase 1-like gene (PPM1l) was identified as causal gene for obesity and metabolic abnormalities in mice. However, the underlying mechanisms were unknown. In this report, we find PPM1l encodes an endoplasmic reticulum (ER) membrane targeted protein phosphatase (PP2Ce) and has specif...

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Detalhes bibliográficos
Main Authors: Lu, Gang, Ota, Asuka, Ren, Shuxun, Franklin, Sarah, Rau, Christoph D., Ping, Peipei, Lane, Timothy F., Zhou, Z. Hong, Reue, Karen, Lusis, Aldons J., Vondriska, Thomas, Wang, Yibin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854994/
https://ncbi.nlm.nih.gov/pubmed/24327956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.07.005
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