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Genome-Wide Gene Set Analysis for Identification of Pathways Associated with Alcohol Dependence

It is believed that multiple genetic variants with small individual effects contribute to the risk of alcohol dependence. Such polygenic effects are difficult to detect in genome-wide association studies that test for association of the phenotype with each single nucleotide polymorphism (SNP) indivi...

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Autori principali: Biernacka, Joanna M., Geske, Jennifer, Jenkins, Gregory D., Colby, Colin, Rider, David N., Karpyak, Victor M., Choi, Doo-Sup, Fridley, Brooke L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854955/
https://ncbi.nlm.nih.gov/pubmed/22717047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145712000375
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