Alpha-1 Antitrypsin Reduces Severity of Pseudomonas Pneumonia in Mice and Inhibits Epithelial Barrier Disruption and Pseudomonas Invasion of Respiratory Epithelial Cells

Nosocomial pneumonia (NP) is the third most common hospital-acquired infection and the leading cause of death due to hospital-acquired infection in the US. During pneumonia and non-pneumonia severe illness, respiratory tract secretions become enriched with the serine protease neutrophil elastase (NE...

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Detalhes bibliográficos
Main Authors: Pott, Gregory B., Beard, K. Scott, Bryan, Courtney L., Merrick, Daniel T., Shapiro, Leland
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Public Health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854847/
https://ncbi.nlm.nih.gov/pubmed/24350188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpubh.2013.00019
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