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α-1-Antitrypsin is an endogenous inhibitor of proinflammatory cytokine production in whole blood

Several observations suggest endogenous suppressors of inflammatory mediators are present in human blood. α-1-Antitrypsin (AAT) is the most abundant serine protease inhibitor in blood, and AAT possesses anti-inflammatory activity in vitro and in vivo. Here, we show that in vitro stimulation of whole...

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Detalhes bibliográficos
Main Authors: Pott, Gregory B., Chan, Edward D., Dinarello, Charles A., Shapiro, Leland
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669404/
https://ncbi.nlm.nih.gov/pubmed/19197072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0208145
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