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α1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice

Human pancreatic islet transplantation offers diabetic patients tight glucose control but has low graft survival rates. The immunosuppressive drugs that are administered to graft recipients lack the antiinflammatory benefits of corticosteroids because of their diabetogenic effects. The serum proteas...

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Detalhes bibliográficos
Main Authors: Lewis, Eli C., Mizrahi, Mark, Toledano, Michel, DeFelice, Nathaniel, Wright, Joanne L., Churg, Andrew, Shapiro, Leland, Dinarello, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2566995/
https://ncbi.nlm.nih.gov/pubmed/18852465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807627105
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