A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Polypodia Mice

Mouse early transposon insertions are responsible for ∼10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan morphogenesis. Our new data shows that mutant mice...

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Detalhes bibliográficos
Main Authors: Lehoczky, Jessica A., Thomas, Peedikayil E., Patrie, Kevin M., Owens, Kailey M., Villarreal, Lisa M., Galbraith, Kenneth, Washburn, Joe, Johnson, Craig N., Gavino, Bryant, Borowsky, Alexander D., Millen, Kathleen J., Wakenight, Paul, Law, William, Van Keuren, Margaret L., Gavrilina, Galina, Hughes, Elizabeth D., Saunders, Thomas L., Brihn, Lesil, Nadeau, Joseph H., Innis, Jeffrey W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854779/
https://ncbi.nlm.nih.gov/pubmed/24339789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003967
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