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A Novel Intergenic ETnII-β Insertion Mutation Causes Multiple Malformations in Polypodia Mice

Mouse early transposon insertions are responsible for ∼10% of spontaneous mutant phenotypes. We previously reported the phenotypes and genetic mapping of Polypodia, (Ppd), a spontaneous, X-linked dominant mutation with profound effects on body plan morphogenesis. Our new data shows that mutant mice...

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Autors principals: Lehoczky, Jessica A., Thomas, Peedikayil E., Patrie, Kevin M., Owens, Kailey M., Villarreal, Lisa M., Galbraith, Kenneth, Washburn, Joe, Johnson, Craig N., Gavino, Bryant, Borowsky, Alexander D., Millen, Kathleen J., Wakenight, Paul, Law, William, Van Keuren, Margaret L., Gavrilina, Galina, Hughes, Elizabeth D., Saunders, Thomas L., Brihn, Lesil, Nadeau, Joseph H., Innis, Jeffrey W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854779/
https://ncbi.nlm.nih.gov/pubmed/24339789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003967
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