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A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK)

AMPK is a conserved heterotrimeric serine-threonine kinase that regulates anabolic and catabolic pathways in eukaryotes. Its central role in cellular and whole body metabolism makes AMPK a commonly proposed therapeutic target for illnesses characterized by abnormal energy regulation, including cance...

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Detalhes bibliográficos
Main Authors: Sinnett, Sarah E, Sexton, Jonathan Z, Brenman, Jay E
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Open 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854666/
https://ncbi.nlm.nih.gov/pubmed/24396733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/2213988501307010030
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