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Target-directed catalytic metallodrugs

Most drugs function by binding reversibly to specific biological targets, and therapeutic effects generally require saturation of these targets. One means of decreasing required drug concentrations is incorporation of reactive metal centers that elicit irreversible modification of targets. A common...

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Detalhes bibliográficos
Main Authors: Joyner, J.C., Cowan, J.A.
Formato: Artigo
Idioma:Inglês
Publicado em: Sociedade Brasileira de Medicina Tropical 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854446/
https://ncbi.nlm.nih.gov/pubmed/23828584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20133086
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