SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway

Chronic inflammation induced by amyloid-beta (Aβ) plays a key role in the development of age-related macular degeneration (AMD), and matrix metalloproteinase-9 (MMP-9), interleukin (IL)-6, and IL-8 may be associated with chronic inflammation in AMD. Sirtuin 1 (SIRT1) regulates inflammation via inhib...

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Bibliografiske detaljer
Main Authors: Cao, L., Liu, C., Wang, F., Wang, H.
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica 2013
Fag:
Biomedical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854412/
https://ncbi.nlm.nih.gov/pubmed/24036938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20132903
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