p16 (INK4a) has clinicopathological and prognostic impact on oropharynx and larynx squamous cell carcinoma

CDKN2A encodes proteins such as p16 (INK4a), which negatively regulate the cell-cycle. Molecular genetic studies have revealed that deletions in CDKN2A occur frequently in cancer. Although p16 (INK4a) may be involved in tumor progression, the clinical impact and prognostic implications in head and n...

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Autors principals: Silva, S.D., Nonogaki, S., Soares, F.A., Kowalski, L.P.
Format: Artigo
Idioma:Inglês
Publicat: Sociedade Brasileira de Medicina Tropical 2012
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854204/
https://ncbi.nlm.nih.gov/pubmed/22948376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S0100-879X2012007500140
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