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p16 (INK4a) has clinicopathological and prognostic impact on oropharynx and larynx squamous cell carcinoma

CDKN2A encodes proteins such as p16 (INK4a), which negatively regulate the cell-cycle. Molecular genetic studies have revealed that deletions in CDKN2A occur frequently in cancer. Although p16 (INK4a) may be involved in tumor progression, the clinical impact and prognostic implications in head and n...

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Bibliografische gegevens
Hoofdauteurs: Silva, S.D., Nonogaki, S., Soares, F.A., Kowalski, L.P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Sociedade Brasileira de Medicina Tropical 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854204/
https://ncbi.nlm.nih.gov/pubmed/22948376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S0100-879X2012007500140
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