Human immunoglobulin selection associated with class switch and possible tolerogenic origins for Cδ class-switched B cells

Current paradigms of peripheral B cell selection suggest that autoreactive B cells are controlled by clonal deletion, anergy, and developmental arrest. We report that changes to the human antibody repertoire likely resulting from these mechanisms both for a well-characterized autoreactivity from ant...

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Hauptverfasser: Zheng, Nai-Ying, Wilson, Kenneth, Wang, Xiaojian, Boston, Angela, Kolar, Grant, Jackson, Stephen M., Liu, Yong-Jun, Pascual, Virginia, Capra, J. Donald, Wilson, Patrick C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2004
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC385404/
https://ncbi.nlm.nih.gov/pubmed/15085198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420255
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